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New England Patriots offensive tackle Isaiah Wynn blocks during an NFL football game against the Miami Dolphins at Gillette Stadium, Sunday, Sept. 13, 2020 in Foxborough, Mass. (Winslow Townson/AP Images for Panini)
New England Patriots offensive tackle Isaiah Wynn blocks during an NFL football game against the Miami Dolphins at Gillette Stadium, Sunday, Sept. 13, 2020 in Foxborough, Mass. (Winslow Townson/AP Images for Panini)
Andrew Callahan
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After 12 days away, the Patriots activated left tackle Isaiah Wynn off COVID-19 reserve and elevated practice-squad offensive lineman James Ferentz on Saturday.

Wynn was originally placed on COVID-19 reserve with left guard Mike Onwenu on Oct. 4. He has not practiced or played since. Onwenu returned to practice on Thursday and could play Sunday against the Cowboys.

If Onwenu is unavailable, Ferentz should start for a second straight week. Ferentz and interior backup Ted Karras manned both guard spots during every snap of the Patriots’ 25-22 win at Houston. The Pats will be missing right guard Shaq Mason for a second straight game. Mason was ruled out Friday with an abdomen injury, indicating Karras will start again.

An abdomen injury might also sideline backup offensive tackle Justin Herron, who missed practice Thursday and was limited Friday. Herron started in Wynn’s place against the Texans. If he and Wynn are both out versus Dallas, third-string tackle Yodny Cajuste could be tasked with protecting Mac Jones’ blind side in a critical game.